While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. The studies that do exist show mixed results (some show Nonetheless, despite the lack of clinical studies, rheumatologists feel that hydroxychloroquine may have a potential beneficial effect in helping patients with symptoms of fatigue and achiness, which are common complaints in patients with Sjögren’s. Plaquenil for connective tissue disease Plaquenil for erosive osteoarthritis Leflunomide brand name Arava is a rheumatoid arthritis drug that has been prescribed off-label for the treatment of psoriatic arthritis. Leflunomide, which comes in a pill, is beneficial to some people with psoriatic arthritis, according to recent medical studies. PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug summaries are available free of charge and serve as a great resource for US based MDs, DOs, NPs and PAs in patient practice Off Label Therapies. An Off Label Therapy is an FDA-Approved drug for an unapproved use. Before drugs can be approved for a specific use, the company who owns the drug must “submit clinical data and other information to the FDA for review. The good news is that hydroxychloroquine targets the immune system without causing an increase in the risk of infection or cancer that can be seen with other immunosuppressant medications. How the drug works is unclear, but recent research has pointed to an inhibitory effect on toll-like receptors that are proteins involved with inflammation. Off label plaquenil Minocycline for Rheumatoid Arthritis An Antibiotic Protocol, Plaquenil hydroxychloroquine sulfate dose, indications. Plaquenil immunosuppressant side effectsPlaquenil to treat mouth diseasePlaquenil dosages Caution should be exercised when administering PLAQUENIL to nursing women. It has been demonstrated that hydroxychloroquine administered to nursing women is excreted in human milk and it is known that infants are extremely sensitive to the toxic effects of 4-aminoquinolines. GoToSource. Off-label Uses Plaquenil OFF-LABEL SEARCH -. Commonly Prescribed Sarcoidosis Medications — Foundation for.. Hydroxychloroquine Plaquenil Success, Reviews and Side Effects. Apr 09, 2007 I've had CFS since January 2003 with no positive response to many treatments so far. My rheumatologist just prescribed Plaquenil and has high hopes it will do me some good. I was told it's used to treat Malaria but now has off-label use in people with suspected immune deficiencies. My doctor. I've had CFS since January 2003 with no positive response to many treatments so far. My rheumatologist just prescribed Plaquenil and has high hopes it will do me some good. I was told it's used to treat Malaria but now has off-label use in people with suspected immune deficiencies. My doctor. May 23, 2016 What is Plaquenil and what are its benefits for Sjögren’s patients? Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s.