The pharmacist said there wont be any danger just stopping it. Has anyone gone off the plaquenil and what happened? I was put on Plaquenil for RA as I was being dx for lupus. My rhuemy wants me to stop every time I have an infection. Best of luck, Creekbank My mom said she read that plaquenil is mainly used for the discoid lupus and people with the joint pain. Right now my hips are the only thing that is really bothering me my knees are now starting to act up..... Surgery while taking plaquenil Chloroquine aralen should be administered how I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. There is a similar posting on Healthunlocked, "Why oh why did u stop taking plaquenil." You may want to check it out. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. If you are taking hydroxychloroquine for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you. There is no taper needed or withdrawal, but if it has been helping you, you may have increased symptoms by the time you go for your next appointment. If so, you would likely be able to get a prescription from that doctor for one month's supply to tide you over. I have only taken it once, so I am not sure what the results will be. I stopped mine and went into a life threatening flare - I would call your PCP to get a refill You may be fine or not- depends on if your illness has been lurking in the background waiting for an opportunity to launch an attack Louters, I went to see a new rheum and he took me off the Plaquenil to see what symptoms would show. I agree with poobie and would call your pcp to get a refill if possible. Stopping hydroxychloroquine Hydroxychloroquine, the drug that could stop COVID-19 - archyde, Hydroxychloroquine Plaquenil Plaquenil retionpathyIcd 10 code for long term use of plaquenil Stopping prevention or treatment too soon may lead to infection or a return of the infection. Inform your doctor if your condition persists or worsens. It may take several weeks or months to see improvement if you are taking this for lupus or arthritis. Hydroxychloroquine may not prevent malaria in all cases. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects.. Hydroxychloroquine MedlinePlus Drug Information. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Jun 09, 2006 Rheumatoid arthritis RA, the most common form of inflammatory arthritis, can lead to significant pain, disability, and deformity, and is a multisystem autoimmune disorder. The hallmark of this disease, erosive joint destruction, results from unchecked synovial inflammation, which can damage articular cartilage and bone, with resultant loss of. May 07, 2012 Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions.