Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take chloroquine with all of your drugs and health problems. Plaquenil for autoimmune disorders Plaquenil vs generic hydroxychloroquine Hydroxychloroquine in g6pd deficiency What is chloroquine chemoprophylaxis The sulfate and phosphate salts of chloroquine have both been commercialised as antimalarial drugs. Hydroxychloroquine has also been used as an antimalarial, but in addition is now broadly used in autoimmune diseases such as lupus and rheumatoid arthritis. Irreversible retinal damage observed in some patients; significant risk factors for retinal damage include daily doses of chloroquine phosphate 2.3 mg/kg of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some concomitant drug products such as tamoxifen citrate, and concurrent macular disease. Mechanism of Action Chloroquine, a 4-aminoquinoline, is an anti-protozoal agent. The precise mechanism by which chloroquine exhibits activity is not known. Chloroquine, may exert its effect against Plasmodium species by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. For all uses of chloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Chloroquine phosphate mechanism of action Chloroquine Indications, Side Effects, Warnings -, Aralen, Chloroquine phosphate chloroquine dosing. Plaquenil and hair lossDoes plaquenil contain sulfatePlaquenil plateletsChloroquine tablet pricePlaquenil and eye damage You should know that the 150mg base tablet is the same as the 250mg salt tablet and the 300mg base. tablet is the same as the 500mg salt tablet. It is just two different ways of describing the same thing. Chloroquine can be prescribed for either prevention or treatment of malaria. Medicines for the Prevention of Malaria While Traveling.. CHLOROQUINE PHOSPHATE, USP. Chloroquine Phosphate chloroquine phosphate dose.. Mechanism of Action. Chloroquine is an antimalarial agent. While the drug can inhibit certain enzymes, its effect is believed to result, at least in part from its interaction with DNA. However, the mechanism of plasmodicidal action of chloroquine is not completely certain. Mechanism of Action Chloroquine, a 4-aminoquinoline, is an anti-protozoal agent. The precise mechanism by which Chloroquine exhibits activity is not known. Chloroquine, may exert its effect against Plasmodium species by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. Full text Full text is available as a scanned copy of the original print version. Get a printable copy PDF file of the complete article 601K, or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.