Although I take Enbrel, and MTX, neither one work as well as the Plaquenil and the fatigue and joint pain have returned full force. I had to get off of plaquenil as well b/c of toxicity and benign tumors behind my eyes. I'm just wondering if any of you here have had to stop taking Plaquenil and if so what you replaced it with? Not knowing what your dx is, I don't know what to tell you. I haven't found a replacement except that I started my cytoxan every month now. Does hydroxychloroquine cause weight gain Plaquenil granuloma annulare Plaquenil cdc Plaquenil arthritis australia I had an allergic reaction to plaquenil when I was first diagnosed with lupus. My rheumatologist put me on chloroquine and I have been on that for the last 5 years. My flare ups have been minimal on the chloroquine. I do have to go for eye checks just like plaquenil. But I’ve had good luck with this so far. Maybe it’s worth a try! Goodluck. Apr 12, 2013 Quercetin QU is a kind of natural flavonoids, with lipid-lowering, anti-inflammatory and other pharmacological activities, and minor toxic side effects. Thus, we assume that QU may be an adjuvant natural drug for treatment of RA. I "know" I need some meds, but cannot tolerate Plaquenil. Wondering if anyone has come across something "natural" that mimics it. Thanks & LIGHT*****carole - Hi, Carole. I also seem to be having a lot of anxiety and I never had this before I stopped my Plaq Am I just losing my mind? All I can do is offer you my sympathy and suggest you talk to your rheumy or hope that others here have an answer for you. I found that some of my symtoms came back after I got off of plaquenil too but I never found something to really "replace it" unforntunately. Yes I do get some kind of strange migraines but without the pain??? (If anything) Since stopping it even the sun is now my worst enemy and I have had to get a pair of sun glasses.. Hi momto3, Wow, I hate to hear that you had to stop taking plaquenil. Since you're taking Enbrel and MTX, I suppose you have RA and I can't imagine having that and not being able to take plaquenil. I have suffered with migraines for thirty years and the only true relief I've ever gotten are from accupuncture and immitrex. I've had other problems as well but I don't think those would help you b/c they are more related to SLE. Natural alternatives plaquenil Natural alternatives to domperidone? Antiemetics Nausea., Quercetin A Potential Natural Drug for Adjuvant Treatment of. Voltaren pills vs plaquenilChloroquine diphosphate salt autophagyGougerot sjogren traitement plaquenilDo plaquenil and topamax interfere with each other The alternative to Plaquenil is a slightly different anti malarial called Quinacrine. Plaquenil replaced Quinacrine formerly called Atabrine for anti malarial prophylaxis so now the Quinacrine has to be made up into pills or gel capsules by a compounding pharmacy. If you google you will find details of compounding pharmacies. Discontinued Plaquenil.other options?. Natural" alternative to Plaquenil. - HealthBoards. Ways to Heal Systemic Lupus Naturally -. The two types of antimalarials most often prescribed today for lupus are hydroxychloroquine Plaquenil® and chloroquine Aralen®. Unlike the rapid response seen with steroids, it may take months before antimalarial drugs improve your lupus symptoms. Side effects from antimalarials are rare and usually mild. From my research, Plaquenil is one of the most gentle of the disease-modifying drugs, so it's less likely to leave you at risk of infection. One known serious side-effect that happens to something like 1 in 5,000 people after many years of use is that it can cause retinal deposits, which can affect vision. My rheumy has just prescribed Plaquenil for my SS. Reading the warnings, I see that there is concern about effects on the eyes retinas. I am very concerned about this and am wondering if anyone out there has been put on an alternative drug to treat their SS. I have several issues with my.