It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil and folic acid A patient recieving plaquenil therpay but tells the nurse Hydroxychloroquine has also been used as therapy of porphyria cutanea tarda where it seems to act by increasing excretion of porphyrins. Hydroxychloroquine is available in generic forms and under the brand names of Plaquenil in tablets of 200 mg. The usual dose is 400 mg daily in one or two divided doses. Plaquenil Toxicity is due to its affinity for melanin-containing structures in body. With prolonged usage, metabolites of drug accumulate in the retina. May be administered for a few days to acidify the urine to help promote urinary excretion in cases of both overdosage and sensitivity. MALARIA Actions Like chloroquine phosphate, USP, PLAQUENILis highly active against the erythrocytic forms of P. vivax and P. malariae and most strains of P. falciparum but not the gametocytes of P. falciparum. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Plaquenil excretion Plaquenil hydroxychloroquine sulfate dosing, indications., Plaquenil Toxicity - Symptoms, Treatment, Risk Factors, Retinopathy Chloroquine overdose symptomsDosage of plaquenil for 160 lb femalePlaquenil shortage 2019Hydroxychloroquine eyesightPlaquenil and eyesight Fractional Excretion of Sodium FENa Determines if renal failure is due to pre-renal, intrinsic, or post-renal pathology. Plaquenil Dosing Calculator. MDCalc - Medical calculators, equations, scores, and guidelines. PLAQUENIL HYDROXYCHLOROQUINE SULFATE, USP WARNING.. Plaquenil Tablets - NPS MedicineWise. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. PLAQUENIL is indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. Rheumatoid Arthritis PLAQUENIL is indicated for the treatment of acute and chronic rheumatoid arthritis in adults. Acidification of the urine boosts kidney excretion of the 4-aminoquinoline materials. Plaquenil hydroxychloroquine is made use of to treat or avoid fever and ague, an illness triggered by bloodsuckers that enter the physical body via the bite of a mosquito.