Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Taking plaquenil Side effects of plaquenil on eyes Guidelines for Treatment of Malaria in the United States. Regimens used to treat chloroquine -resistant infections may also be used if chloroquine and hydroxychloroquine are not available. Note that if treating. chloroquine-resistant malaria species. Artemether-lumefantrine Coartem™ Malaria can be treated effectively early in the course of the disease but that delay of appropriate therapy can have serious or even fatal consequences Travelers who have symptoms of malaria should be advised to seek prompt medical evaluation, including obtaining blood smears, as soon as possible People with falciparum malaria may need to be monitored in the intensive care unit of a hospital during the first days of treatment because the disease can cause breathing failure, coma and kidney failure. For pregnant women, chloroquine is the preferred treatment for malaria. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine-resistant malaria may be treated with __________ Chloroquine-Resistant Malaria – Page 2 –, Malaria Flashcards Quizlet Indication of chloroquine in pregnancy The combination of atovaquone and proguanil is highly effective for the prophylaxis and treatment of chloroquine-resistant malaria. Artemether/lumefantrine inhibits CYP2D6 and can raise the levels of drugs that are substrates for this enzyme, including imipramine. Artesunate is an investigational drug used for severe malaria. Chapter 98 Antiprotozoal Drugs I Antimalarial Agents.. Malaria Guide Causes, Symptoms and Treatment Options. Can amoxicillin be used to treat malaria? -. Your options for malaria prophylaxis may include. Quinine This drug is used to treat chloroquine-resistant malaria. Quinine is derived from the cinchona tree of South America. For the prevention of chloroquine-resistant malaria, mefloquine is one of several options, along with atovaquone-proguanil, doxycycline or primaquine Footnote 65. Although chloroquine resistance may re-emerge if used as monotherapy for treatment of symptomatic disease, chloroquine may be a desirable option for prevention of malaria during pregnancy or for chemoprophylaxis in infants and children.