Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil antacids Plaquenil for pregnancy loss Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease Slit-lamp examination showed a whorl-like pattern of corneal epithelial deposits bilaterally, characterizing amiodarone-induced vortex keratopathy. Tommy C. Y. Chan, M. B. B. S. Vortex whorl keratopathy. The aminoquinoline antimalarial drugs amodiaquine, chloroquine, mepacrine quinacrine, and hydroxychloroquine Plaquenil® are another common cause of drug-induced corneal deposits. Hydroxychloroquine is frequently used in the United States to treat rheumatoid arthritis and lupus erythematosus. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Whorl keratopathy plaquenil Ocular side effects of anti-rheumatic medications what a., Amiodarone-Induced Vortex Keratopathy NEJM Chikungunya disease and chloroquine treatmentEffect of plaquenil on eyes Plaquenil 必賴克瘻. The cornea may become affected relatively commonly by an innocuous vortex keratopathy and is characterized by whorl-like corneal epithelial deposits. These changes bear no relationship to dosage and are usually reversible on cessation of hydroxychloroquine. RA 認識 免疫調節藥 - Hydroxychloroquine HCQ -.. Drug-induced corneal epithelial changes - ScienceDirect. Glaucoma Diabetic Eye Disease Laser Surgery PLAQUENIL.. Chloroquine CQ is used to prevent and treat malaria and amebiasis,1 while hydroxychloroquine HCQ, a less toxic metabolite of chloroquine, is used to treat rheumatic diseases such as systemic lupus erythematosus SLE, rheumatoid arthritis RA, juvenile idiopathic arthritis JIA and Sjogren's syndrome.2 Both medications can cause corneal deposits, posterior subcapsular lens opacity. Chloroquine toxicity is characterized by whorl-like corneal epithelial deposits. Etiology Medications of the chloroquine family, including chloroquine Nivaquine, Avloclor, hydroxychloroquine Plaquenil, and amodiaquine, have been associated with keratopathy Srinivasan et al. 2011. The patient reported being diagnosed with systemic lupus erythematosus SLE two years prior and secondary kidney and liver dysfunction. She said she was treated with 200mg to 400mg of Plaquenil hydroxychloroquine sulfate, Sanofi-Synthelabo per day for her lupus 4.4mg/kg to 8.8 mg/kg per day for two years with a cumulative dose of 276g. The patient said she was also prescribed prednisone for her lupus; the dose had been tapered from 5mg/day to 1mg/day.