It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Nifedipine and hydroxy chloroquine side effects Is hydroxychloroquine safe in pregnancy Plaquenil and atrial fibrillation Plaquenil side effects neuropathy What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Hydroxychloroquine can cause irreversible retinal toxicity, resulting in bilateral bull’s eye retinopathy, but is regarded as less toxic to the retina than chloroquine and it does not cause the corneal deposits seen with chloroquine therapy. Commonly used on holidays in malaria prone destinations, chloroquine and hydroxychloroquine will not be over familiar to the emergency physician. However, it is one of the leading causes of drug overdose in malaria prone countries and also the occasional toddler has managed to consume the grandparents lupus or rheumatoid arthritis medication leading to lethal consequences. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Hydroxychloroquine intoxication UpToDate, Hydroxychloroquine DermNet NZ Can swollen ankles be caused by hydroxychloroquineHow does plaquenil treat lupusPlaquenil 200 in pregnancyReactions to plaquenil Lyons emphasizes the importance of annual screening and says that, although annual screening is recommended for everyone taking Plaquenil, it is imperative for people who have been taking the medication for more than 10 years, who have a higher incidence of retinal toxicity. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. Protecting your eyesight when taking Plaquenil Lupus.. Chloroquine and Hydroxychloroquine • LITFL • Toxicology.. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Hydroxychloroquine has also been used as an antimalarial, but in addition is now broadly used in autoimmune diseases such as lupus and rheumatoid arthritis. Of note, chloroquine and hydroxychloroquine are considered to be safe and side-effects are generally mild and transitory.