Chloroquine hydrochloride formulation

Discussion in 'Chloroquine Online' started by bber, 18-Mar-2020.

  1. Ojober XenForo Moderator

    Chloroquine hydrochloride formulation


    It contains, in each m L, not less than 47.5 mg and not more than 52.5 mg of C To 20 m L of a dilution of Injection with water, containing about 20 mg of chloroquine hydrochloride, add 5 m L of trinitrophenol TS: a yellow precipitate is formed. Filter, wash the precipitate with water until the last washing is colorless, and dry over silica gel: the precipitate melts between 205 and 210.

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    Action Date Submission Action Type Submission Classification Review Priority; Orphan Status Letters, Reviews, Labels, Patient Package Insert Notes Chloroquine’s spectrum of activity includes the asexual erythrocytic forms of Plasmodium malariae, P.ovale, P. vivax, many strains of P. falciparum, and Entamoeba histolytica. Pharmacokinetics Absorption Absorbed readily and almost completely. Distribution 55% bound to plasma proteins. Concentrated in erythrocytes, liver, spleen, kidneys. If chloroquine hydrochloride is given intravenously, it must be administered by slow, constant infusion to avoid respiratory depression, hypotension, heart block, cardiac arrest and seizures that may occur with transient toxic levels. A dose of 300 mg base q8–12h may be given by intramuscular injection.

    Transfer 5.0 m L of this solution to a 100-m L volumetric flask, add 10 m L of dilute hydrochloric acid (1 in 100), and dilute with water to volume. [ Transfer an accurately measured volume of Injection, equivalent to about 150 mg of chloroquine hydrochloride, to a 1000-m L volumetric flask, and dilute with water to volume.

    Chloroquine hydrochloride formulation

    Centration Comments Reference one Reference Two, Chloroquine hydrochloride - GLOWM

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  3. Chloroquine-resistant malaria may be treated with __________
  4. Chloroquine phosphate may cause an upset stomach. Take chloroquine phosphate with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use chloroquine phosphate exactly as directed. Do not use more or less of it or use it more often than prescribed by your.

    • Chloroquine MedlinePlus Drug Information.
    • Chloroquine - an overview ScienceDirect Topics.
    • Chloroquine hydrochloride - DrugBank.

    Stability of alprazolam, chloroquine phosphate, cisapride, enalapril maleate, and hydralazine hydrochloride in extemporaneously compounded oral liquids. Am J Health-Syst Pharm. 1998;55181915-1920. Aminophylline Chong E, Dumont RJ, Hamilton DP, Koke PM, Ensom MHH. Stability of aminophylline in extemporaneously-prepared oral suspensions. Chloroquine hydrochloride USP View Synonyms View Structure Description The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses. Find patient medical information for Chloroquine Injection on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

     
  5. webwildathletic Well-Known Member

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