One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Does chloroquine increase the effects of digoxin Receptor tyrosine kinase dengue virus chloroquine Hydroxychloroquine arthritis treatment Jun 14, 2017 Do you know the current screening recommendations for patients on Plaquenil? Which tests should you choose and when? Risk factors for toxicity are high dose, long duration, renal disease and tamoxifen. If you are coming to the OA July Scientific Meeting July 29th Red Hill, you will hear more about Plaquenil toxicity. Mar 01, 2011 The new guidelines recommend 10-2 automated perimetry, plus at least one of SD-OCT, FAF, or mfERG if they are available. These tests should be performed at baseline and at each subsequent evaluation. Other tests may be considered as well, but are generally insufficiently sensitive to detect early evidence of hydroxychloroquine toxicity. The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity 1. According to these new guidelines, the risk of HCQ retinal toxicity is less than 1 % in the first year of therapy and less than 2 % up to 10 years of therapy. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Aao guidelines for plaquenil New Plaquenil Guidelines, New Screening Guidelines for Hydroxychloroquine Toxicity Hydroxychloroquine and skin discolorationHydroxychloroquine and lorazepamRheumatoid arthritis choosing initial treatment plaquenil vs enbrelPlaquenil safer than floroquinolones Preferred Practice Pattern® Guidelines. Preferred Practice Pattern® guidelines "PPP" are designed to identify characteristics and components of quality eye care. Developed by a panel of ophthalmologists with expertise in the guideline topic, a methodologist, and other experts the Quality of Care Secretariat and the PPP Committee. Preferred Practice Pattern® Guidelines - American Academy of.. New Guidelines on Hydroxychloroquine Dosage - Where Are We.. Quick Reference Screening for Chloroquine.. Abstract Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. If you are already familiar with plaquenil and the AAO guidelines, skip the background section and go to the pertinent questions section that follows. Background. Plaquenil hydroxychloroquine is an anti-inflammatory drug used in the treatment of malaria and in the treatment of rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.