Chloroquine resistant malaria treatment in children

Discussion in 'Hydroxychloroquine Sulfate' started by VladimirOvechkin, 05-Mar-2020.

  1. Bandit79 XenForo Moderator

    Chloroquine resistant malaria treatment in children


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Drug resistance in Africa versus Asia. While chloroquine-resistant malaria was rapidly outcompeted after the removal of chloroquine as the first-line treatment in Malawi, a similar return of chloroquine-susceptible infections has not been observed in Asia. Chloroquine CQ continues to be the first-line medication used worldwide in the treatment of Plasmodium vivax malaria. The dose recommended by the World Health Organization is 25 mg/kg independently of the age of the subject. Nonetheless, the. In patients for whom the likelihood of chloroquine-resistant P. vivax is high, mefloquine or quinine/quinidine plus doxycycline for patients 7 years of age may be used 28, 30. In patients with P. vivax or P. ovale malaria, the initial treatment regimen should be followed by treatment with primaquine “radical cure”. Primaquine is.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine resistant malaria treatment in children

    Chloroquine - Wikipedia, Evaluation of the paediatric dose of chloroquine in the.

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  4. TREATMENT OF MALARIA INFECTION. Single-agent monotherapy approaches to malaria treatment are a major contributor to drug resistance and are not recommended. 32 In general, antimalarial decision-making is based on severity of symptoms, parasite species, and likelihood of drug resistance Fig. 3.

    • Malaria in Children.
    • Diagnosis and Treatment of Malaria in Children Clinical..
    • Chloroquine Oral Uses, Side Effects, Interactions, Pictures, Warnings..

    In addition, any of the regimens listed below for the treatment of chloroquine-resistant malaria may be used for the treatment of chloroquine-sensitive malaria. Prompt initiation of an effective regimen is vitally important and so using any one of the effective regimens that is readily at hand would be the preferred strategy. Chloroquine phosphate or hydroxychloroquine sulfate can be used for prevention of malaria only in destinations where chloroquine resistance is not present see Maps 2-7 and 2-8 or the next section in this chapter, Malaria Risk Information and Prophylaxis, by Country. New evidence that doxycycline may be considered for treatment of malaria in children under 8 years when there are no other alternative options ; For the prevention of chloroquine-resistant malaria, mefloquine is now listed as one of several options, along with atovaquone-proguanil, doxycycline or primaquine

     
  5. Luu Moderator

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  6. Vovan_ New Member

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  7. sanya777777777 Moderator

    Plaquenil Risk Calculators A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity.

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