Hydroxychloroquine recurrent miscarriage

Discussion in 'Hydroxychloroquine' started by Vlad7090, 15-Mar-2020.

  1. OneLive XenForo Moderator

    Hydroxychloroquine recurrent miscarriage


    sso-checked=true I'm six weeks pregnant and jumped in this convo because I had just read a study where in some t ypes of APA's, Lovenox and Bany Aspirin are not enough. If we can't afford IVIG and insurance (of course) will not cover it, would Plaquenil be beneficial as well for those specific antibodies? I was borderline positive on a few and positive for one of the Lupus anticoagulants.

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    My recurrent miscarriage consultant is keen for the hydroxychloroquine and my IVF clinic advises the prednisolone.already taken the prednisolone while pregnant and still had a miscarriage so keen for something more. Will also have clexane this time as well as aspirin. Recurrent miscarriage is frustrating for the physician and a heartbreaking experience for the patient. Approximately 5% of couples trying to conceive have two consecutive miscarriages. Despite a thorough study of patients, the aetiology of this common obstetric complication is unknown in 50% of cases. Hydroxychloroquine during pregnancy reduces the risk of cardiac NLS in at-risk fetuses 45, 79. The recurrence risk of CHB in subsequent pregnancies after an affected pregnancy is many-fold higher. Hydroxychloroquine reduced this risk by 65% in one study 45.

    I would be very suspect for anti paternal HLA antibodies here which are not necessarily 'auto" abs, and IVIG and lovenox and prednisone would be the best treatments. First I can make no recommendations without a thorough history and evaluation of your case.

    Hydroxychloroquine recurrent miscarriage

    Hydroxychloroquine for Prevention of Recurrent Miscarriage. - Full Text., Recurrent miscarriage causes, evaluation and management.

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  3. Jan 09, 2015 2026 Posts RE Plaquenil Hydroxychloroquine during pregnancy Posted on Jan 9, 2015 at pm not the first line for NK cells but seems to have benefits there and for those with autoantibody mediated syndromes. Mechanism of action still unclear.

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    Hydroxychloroquine – last chance saloon. I posted earlier in the week with the shitty news that i’d had a fifth miscarriage – my second miscarriage in two months. I’m seeing a specialist in reproductive immunology and made an appointment to see him to discuss what had happened and try and make a plan for what to do next. Oct 21, 2019 Potential mechanisms of action of hydroxychloroquine HCQ in preeclampsia PE and recurrent miscarriage RM and clinical studies HCQ can prevent the occurrence of systemic inflammation in PE and RM by inhibiting lysosomal and extralysosomal TLR. Hydroxychloroquine for prevention of recurrent miscarriage Study protocol for a multicentre randomised placebo-controlled trial BBQ study

     
  4. BS_Zor Guest

    At Healthfully, we strive to deliver objective content that is accurate and up-to-date. These Drugs Can Mess With Your Potassium Levels - GoodRx Does intake of Plaquenil cause an increase in blood sugar. Can plaquenil cause low blood pressure? -
     
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  6. mcdime XenForo Moderator

    Chloroquine Oral Uses, Side Effects, Interactions, Pictures. Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

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