Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil side effects bleeding Chloroquine and g6pd For treating lupus in adults, the recommended starting Plaquenil dosage is 400 mg once or twice a day. After a while, your healthcare provider may recommend a lower dosage such as 200 mg once daily. I also take Mirlax and it's prescribe for me to take it twice a day, everyday. However, again you should check with your Doctor to see how they want you take these medications. I do not take my Mirlax daily, I only take it when I seem to be getting slightly constipated. Welcome to the subreddit. I'm on 200mg twice daily of Plaquenil. I started it in late September of this year. I honestly haven't noticed many side effects of Plaquenil except for, in the beginning, it made me a little nauseous. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. How to take plaquenil twice daily Hydroxychloroquine Side Effects, Dosage, Uses, and More, Bad Side Effects of Plaquenil - Fatal dose of chloroquinePlaquenil induced retinal toxicity Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil Uses, Dosage & Side Effects -. What is/was your experience taking Plaquenil like? rheumatoid. I take Plaquenil 200MG TAB.tablet twice daily I just accidently.. Systemic lupus erythematosus is treated with 400 mg once or twice daily for several weeks then 200-400 mg daily. Hydroxychloroquine should be taken with food or milk in order to reduce stomach upset. Hydroxychloroquine should be taken with food or milk in order to reduce stomach upset. Hi, I saw a rheumy for the first time last week, and he prescribed plaquenil, 200 mg twice a day. Didn't diagnose with Lupus yet, but said I definitely have something autoimmune going on and the plaq will help with the fatigue. He warned that it could take 2-6 months, though, which is what I've read here too. I have been on Plaquenil for about 9 weeks 200mg twice daily. I started seeing some improvement in about 5 weeks. Was told it would take at least 2 months to see noticable improvement. I went to my Rheumy for a follow up at 8 weeks and most of my inflamation is gone.