It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Chloroquine phosphate anemones Chloroquine in first trimester pregnancy Hydroxychloroquine birth defects Hair loss with plaquenil Treatment. Treatment of Lyme arthritis is based on several small, double-blind or randomized studies and observational studies summarized in Table 2. The efficacy of antibiotics was first demonstrated in a double-blind, placebo-controlled trial of IM benzathine penicillin, 2.4 million units weekly for 3 weeks versus placebo. Plaquenil is an antirheumatic drug that helps to modulate an overstimulated immune system and decrease pain and inflammation. It also shown effective in hitting cystic forms of Borrelia burgdorferi and alkalizing the intracellular compartment making antibiotics more effective. Lyme disease is a multisystem illness caused by infection with the spirochete Borrelia burgdorferi and the body's immune response to the infection. The disease is transmitted to humans via tick bites, from infected ticks of the genus Ixodes. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil treatment lyme disease Macrolide therapy of chronic Lyme Disease., What does Plaquenil do? - Plaquenil lupus en espanol Plaquenil is often perceived as an anti-arthritis drug used to treat connective tissue disorders. What it does is make the body more alkaline. My doc explained that he prescribes it with Biaxin Clarithromycin-an intracellular abx because by making the body more alkaline, the Biaxin can more easily penetrate the body's cells, which makes it up to 40% more effective. Plaquenil for treatment - Lyme Disease - MedHelp. Lyme Disease Treatment & Management Approach Considerations.. Hydroxychloroquine Plaquenil. Plaquenil itself is an antibiotic and antibiotics itself do not seem following some experiments to do any good with treating lyme. But doctors found that cellular Ph the degree of acidity needs to be changed, meaning maximize or minimize the level of Ph, in order that antibiotic could work better. Indefinite long-term treatment is advocated by ILADS International Lyme and Associated Diseases Society, based on a patient’s symptoms. In contrast, IDSA Infectious Disease Society of America only recommends 2-4 weeks' treatment. The two groups are bitter adversaries. Hi, I have lyme disease and have frequently been on plaquenil only in the summer as stronger drugs are used when I'm not in the sun and I've yet to experience this. But I do know that it is often used to prevent and treat malaria and that many drugs that deal with such things have a tendency to cause some crazy dreams.