It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Chloroquine fas associated Hero study hydroxychloroquine Aug 02, 2010 Plaquenil works by suppressing the immune system. Unfortunately you can't tell it to attack just the germs so you suppress all of its function to spare your healthy tissue- in your husband's case, his eyes, mouth, throat. NOTE Plaquinil and hydroxychloroquine are essentially the same drug. The same effects should be expected from both drugs. 2. No, his immune system should not be forever compromised. A recent large study of people with cardiovascular disease found that hydroxychloroquine Plaquenil does not increase the risk of infection and methotrexate increases the risk of infection only slightly. Feb 04, 2015 plaquenil, medicine, chronic, drug. For three months I have cold after cold with chronic and sometimes violent coughing. I have been given many medicines to fight the viruses with little success. I never had this much trouble before taking plaquenil. I was diagnosed with Lupus in April of 2014. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Does plaquenil lower your immune system Reasonably Well Plaquenil FAQ, Coronavirus and Arthritis What You Need to Know Arthritis. Other options for hydroxychloroquine plaquenil Jun 01, 2018 Plaquenil is an immunomodulatory drug DMARD that works by suppressing the immune system to prevent it from damaging tissues and joints. The immune system helps protect the body from harmful substances such as infectious agents and bacteria. Plaquenil. I have been taking plaquenil for almost a year, does this.. What Is Plaquenil? - American Academy of Ophthalmology. Higher doses of medications that weaken your immune system are more likely to increase your risk of getting a fungal infection. 5,11,13,14 Click on the sections below to see lists of corticosteroids and TNF inhibitors that can increase the chances of getting a fungal infection. Mar 23, 2014 Plaquenil is not thought to have a strong effect on the immune system with regard to illnesses etc.far as I am aware. I am sure others will be on to share any similar experiences however, I found the plaquenil, if anything very weak for my MCTD.needed steroids too whilst it was kicking in.then Cellcept etc etc Plaquenil Hydroxychloroquine is used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus & others.