I can't say that the drug has helped at all, but it is difficult to compare todays pain with that of 6 months ago. Still get mysterious rashes, fevers and other odd symptoms. Asked my primary to check my thyroid after taking a bovine herbal thyroid med for 2 weeks. Then they worked out it was my liver causing my liver and that I could go back on Plaquenil. I have gained nearly 25 lbs now and I can' t stand it, but when I try an dexercise it is as if my muscles just will not relax, the are tight and it hurts to even do the lightest yogo! I took 60mg for a year and only 30 this past month. NOw if my thyroid isn't working I've hidden it from my dr... Well, within 3 days my non-liver symptoms were way better. Can hydroxychloroquine cause high blood glucose levels Plaquenil and liver disease Plaquenil and allergy medications Talk to your doctor about this, but my guess is that the Plaquenil is not doing anything to cause the pain, but rather that it is not doing enough to prevent it. It sounds like your RA has probably gotten a bit out of control, relative, to your current treatment, and Plaquenil is not a particularly potent drug when it comes to managing joint pain. Drug-related myotoxicities such as rhabdomyolysis or myoglobinuria are more typically reported, as they are more serious medical emergencies. Rhabdomyolysis is a fulminant and acute, necrotizing myopathy that can cause severe pain, muscle swelling and weakness, and elevated serum CK as high as 2000 times the upper limit of normal. Sep 06, 2017 When a person has an underactive thyroid hypothyroidism, muscle pain is a common symptom. It often occurs due to fluid retention, which can cause the muscle to swell and potentially press on the nerves. General muscle pain, such as cramps and stiffness, is common—particularly in the shoulder and hips. As is arthropathy joint pain, achiness. I saw a rheumatologist who said "no the nausea is at the start before you get use to it etc, but just come off it for 2 weeks to 'prove this doctor wrong'". Don't know what I was thinking but my thyroid showed 1.59 (0,47-4.68)... Since then I've had one flare up of my hips and finger joints, which lasted for about 2-3 days (typically my flares last a few weeks). I'd say they're 90-95% better than this time last year. Plaquenil cause muscle pain Will you have Joint pain with Plaquenil - eHealthMe, Drug-related Myopathies of Which the Clinician Should Be Aware Otezla and plaquenilPlaquenil antimalarial Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. Plaquenil - Uses, Side Effects, Interactions -. Myalgia 6 Common Reasons for Experiencing Muscle Pain.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hi, although Plaquenil is prescribed for autoimmune diseases, such as yours, it can actually add to/increase the number of the symptoms. Muscle damage and leg pain being just 2 examples. It is great that you have responded so well to the new medication. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Do you still have joint and muscle pain on plaquenil? I've been on plaquenil for 6 months now and I still have significant joint pain! I can't say that the drug has helped at all, but it is difficult to compare todays pain with that of 6 months ago.